РОССИЙСКАЯ АКАДЕМИЯ НАУК

УРАЛЬСКОЕ ОТДЕЛЕНИЕ

ИНСТИТУТ ХИМИИ TBEPДОГО ТЕЛА
   
| | | | |
| | | |
 11.03.2008   Карта сайта     Language По-русски По-английски
Новые материалы
Экология
Электротехника и обработка материалов
Медицина
Статистика публикаци


11.03.2008



Miniature mixing inspired by nature



06 March 2008



Dutch scientists have copied nature to develop a faster and more efficient method for mixing small volumes of liquid. They were inspired by micro-organisms that use tiny oscillating hairs (called cilia) to move through liquid, and made artificial cilia to use in microfluidics.


Artificial cilia








Artificial cilia (right) mimic real cilia such as those on a Paramecium micro-organism (left)



Microfluidics is the study of fluid flow in structures with dimensions smaller than a millimetre, with devices as small as a credit card. Key applications for these devices include biochips, especially the immediate point-of-care diagnosis of diseases. The problem with such a small device is that good mixing is almost impossible. Usually, mixing is done by etching grooves into the fluid channels or applying an electrical pulse or sound wave. However, there is no real control over the mixing in these cases, according to Jaap den Toonder of the Philips Research Laboratory in Eindhoven.


Toonder and colleagues have therefore made artificial cilia from a double layer of thin polymer, called polyimide, and a thin conductive layer of chromium. The artificial cilia look a lot like a curled-up leaf.



"Key applications for these devices include biochips, especially the immediate point-of-care diagnosis of diseases."

These tiny mixers are activated by applying a voltage. When applied, the rolled-up cilia uncurl. When the voltage is turned off, the cilia roll back up by elastic recovery. In this way, the mixing can be turned on or off by demand and in any location in the device, an advantage over other mixing methods.


Andreas Manz, head of the Institute for Analytical Sciences in Dortmund, Germany, commented that the use of the artificial cilia for mixing was intriguing, as 'in biological systems cilia are used for transport'.


When questioned about the future, den Toonder said the next steps were to find alternative ways to activate the artificial cilia, such as magnetically-driven systems. The team's final goal is to develop artificial cilia 'into a versatile method for medical diagnostic lab-on-a-chip devices'.


Rebecca Brodie




Link to journal article



Artificial cilia for active micro-fluidic mixing
Jaap den Toonder, Femke Bos, Dick Broer, Laura Filippini, Murray Gillies, Judith de Goede, Titie Mol, Mireille Reijme, Wim Talen, Hans Wilderbeek, Vinayak Khatavkar and Patrick Anderson, Lab Chip, 2008
DOI: 10.1039/b717681c


Дизайн и программирование N-Studio 
А Б В Г Д Е Ё Ж З И Й К Л М Н О П Р С Т У Ф Х Ц Ч Ш Щ Ъ Ы Ь Э Ю Я
  • Chen Wev .  honorary member of ISSC science council

  • Harton Vladislav Vadim  honorary member of ISSC science council

  • Lichtenstain Alexandr Iosif  honorary member of ISSC science council

  • Novikov Dimirtii Leonid  honorary member of ISSC science council

  • Yakushev Mikhail Vasilii  honorary member of ISSC science council

  • © 2004-2019 ИХТТ УрО РАН
    беременность, мода, красота, здоровье, диеты, женский журнал, здоровье детей, здоровье ребенка, красота и здоровье, жизнь и здоровье, секреты красоты, воспитание ребенка рождение ребенка,пол ребенка,воспитание ребенка,ребенок дошкольного возраста, дети дошкольного возраста,грудной ребенок,обучение ребенка,родить ребенка,загадки для детей,здоровье ребенка,зачатие ребенка,второй ребенок,определение пола ребенка,будущий ребенок медицина, клиники и больницы, болезни, врач, лечение, доктор, наркология, спид, вич, алкоголизм православные знакомства, православный сайт творчeства, православные рассказы, плохие мысли, православные психологи рождение ребенка,пол ребенка,воспитание ребенка,ребенок дошкольного возраста, дети дошкольного возраста,грудной ребенок,обучение ребенка,родить ребенка,загадки для детей,здоровье ребенка,зачатие ребенка,второй ребенок,определение пола ребенка,будущий ребенок